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Dogs
Canine Transmissible Venereal Tumor
Canine transmissible venereal tumor, also called
transmissible venereal tumor (TVT), Sticker tumor and
infectious sarcoma is a
tumor of the
dog and other canids that
mainly affects the external
genitalia. In
male dogs, the tumor affects the
penis or
prepuce. In
females, it affects the
vagina or labia.
Rarely, the mouth or nose are affected. The tumor often has a
cauliflowerlike appearance. The disease is spread when dogs mate. The
tumor does not often
metastasize.
Biopsy is necessary
for diagnosis.
Chemotherapy is very effective for this type of tumor, but surgery
often leads to recurrence. The
prognosis for
complete
remission is excellent. Canine TVT was initially described by
Russian
veterinarian Novinsky in
1876, when he
demonstrated that the tumor could be transplanted from one dog to
another by infecting them with tumor cells.
Tumor cells have fewer
chromosomes than
normal cells. Dog cells normally have 78 chromosomes; tumor cells contain 57 -
64 chromosomes.
References
- Ettinger, Stephen J.;Feldman, Edward C.(1995).Textbook of Veterinary
Internal Medicine(4th ed.). W.B. Saunders Company.
ISBN 0-7216-6795-3
- Mello Martins, M.I. 2005.
Canine Transmissible Venereal Tumor: Etiology, Pathology, Diagnosis and
Treatment. In: Recent Advances in Small Animal Reproduction,
Concannon P.W., England G., Verstegen III J. and Linde-Forsberg C. (Eds.).
International Veterinary Information Service, Ithaca NY
- Morrison, Wallace B. (1998). Cancer in Dogs and Cats (1st ed.).
Williams and Wilkins.
ISBN 0-683-06105-4
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